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Re: ED - what are the REAL facts?

Boy, do I hesitate to get involved in this can of worms. But I think one point has te be emphasized. OFA evaluation of hips and elbows are NOT tests, in the sense that the PRA, EIC, and CMN tests are tests. They are evaluations of phenotype and therefore are more similar to evaluation of coat texture, rear leg angulation, etc. The procedure gives us information about phenotype that we can't see from looking at the external structure of the dog. And the information bears directly on the functionality of the dog, which is why most of us think that it is of enough significance to be worth spending some money and taking the results seriously in planning our breeding program. If I care deeply about any particular phenotypic trait, I am going to avoid a dog that doesn't have or doesn't produce that trait. I care deeply about having an orthpedically sound dog, so I avoid breeding to dogs with non-passing hips or elbows. I have not (and I'm knocking on wood here) had any bad elbows in about 10 years since I have been screening for and eliminating non-passing elbows for three generations now, and I started screening in about 1990 after I produced a litter riddled with them. You can get rid of or at least severely reduce the incidence of poor heads, tailsetes etc., by concentrating on eliminating them from your breeding program by the old-fashioned way of selecting parental stock that do not have the trait. Orthopedic problems are no different. You just have to decide what is more important to you, soundness or other characteristics that you are selecting for. I've been fortunate that the dogs I had to eliminate for bad elbows were not the ones I most desperately wanted to keep because of their other traits. I haven't been tempted to use a dog with a grade 1 elbow, for instance, except as a stud dog from someone else's breeding program, and I have decided against several stud dogs because of an elbow that didn't pass even though there may have been an injury involved. Other people have had to make different decisions. But to ignore orthopedic evaluations because they are not definitive tests means that you are ignoring part of the phenotype and telling the rest of us that it is not important in your breeding program.

Re: ED - what are the REAL facts?

Maureen, Your scorn for my intellect and background ring loud and clear. I don't generally find that kind of scorn to be characteristic of trained people. I participate in a national board of professionals in which we discuss in great detail how tests can be validated. I teach in a major medical school where we routinely discuss the validation of tests and their data. And none of these people stoop to the kind of personal attacks that characterize your posts to me. If you are so sure you are right, why not just stick to the facts.

I am not harping on my analysis; I have said that it is a reasonable analysis based on the available data on the website. Nothing more. Nothing less. I used the analysis only to point out that these tests have never received the kind of statistical scrutiny that the Optigen test, or even the EIC test has gotten before we adopted them. I'm not interested in defending it; all manner of people use these kinds of comparisons. For example, my financial advisor just sent me a first quarter earnings report and compared it to both first quarter earnings for last year and total earnings for the year. Simple stuff, really.

Peggy, there are many kinds of tests used by many professional groups; they are not genetic tests, but nongenetic tests too can be validated. In fact, I had to validate and publish a paper and pencil test in order to even begin collecting data for my dissertation years and years ago. There are procedures for validating and examining the heritable components of all manner of tests.

My concern is lack of validation for the OFA tests themselves--not the outcome data. Show me the validation of the effectiveness of these
tests. People who pay as much money for these deserve to know how these tests stack up in defining heritability and how much these tests can contribute
to breeding decisions. (And Maureen, this data is available for PennHIP.) Kate

Re: ED - what are the REAL facts?

Yep... my horoscope was right on target!

Re: Re: ED - what are the REAL facts?

"Maureen, Your scorn for my intellect and background ring loud and clear. I don't generally find that kind of scorn to be characteristic of trained people."

What is Maureen trained in? I didn't think she was in the medical profession.

Re: ED - what are the REAL facts?

Why do you 2 have to always take these subjects up on public boards instead of privately? The dart throwing is not appropriate behavior and the length of postings is tedious to read. We have to sort out the private issues amongst the 2 of you before reading about ED.

Can't you take this into email, an instant messenger or on a telephone call?

Re: ED - what are the REAL facts?

A small addition to this discussion which has nothing to do with actual "math" talk. (breathing a sigh of relief)

One of the bigger problems I see in trying to effectively evaluate the data from OFA on elbows, are those who are not in the database because they do one of three things, get rid of young puppies who limp (send them to pet homes,) don't send in xrays of elbows if they believe they are going to fail or don't publish results if their dog fails elbows.

It would be interesting to see what percentage of labs have hips and not elbows, or elbows and not hips (I bet this number is pretty small) If we made the assumption that all of these dogs failed elbows (or 75% did or pick some number) and included them in the data, what would we then see for change over the last 15 years?

Is the change, if there really is a change, a reflection in better breeding secondary to better information or is there some other explanation we are missing? Stats are what you make of them, there are many ways to mathematically handle numbers and numbers sometimes lie.

Another problem, albeit a lesser one, that I see with elbows, is that any change in the elbow is read as ED, and I am pretty sure some of those are not true ED but rather other events that led to changes in the elbow that are environmental rather than inherited.

Bonnie

Re: ED - what are the REAL facts?

I don't think anyone scorns true intellect; what they scorn is ego, and ego has certainly landed here.

Re: ED - what are the REAL facts?

Bonnie, Given the fact that the elbow dysplasia is judged by evidence of arthritis and sclerosis, false positives (e.g., enviromental accidents and overuse/overloading injuries) are inevitable, especially in large bodied and physically active dogs.

Re: ED - what are the REAL facts?

Kate wrote: "Bonnie, Given the fact that the elbow dysplasia is judged by evidence of arthritis and sclerosis, false positives (e.g., enviromental accidents and overuse/overloading injuries) are inevitable, especially in large bodied and physically active dogs."

Do you think Kate, if we did our elbow evaluations at 6 months rather than 2 years we would cut down on false positives or would we miss too many later developing elbow issues?

(am hoping you are sleeping well and pictures will be available soon!!)

Bonnie

Re: ED - what are the REAL facts?

Bonnie, I really have more questions than answers at
this point about elbows. I'm really trying to figure
out what to do next and gathering information--for myself, my own breeding program. I care about the breed as a whole, but it is my own puppies who really motivate me to be unsatisfied with the status quo.

It would really help if OFA analyzed their available data and could give us some idea about the rate of false positives in their methods and how much their current elbow x-ray really tells us about inheritance of elbow DJD. Clearly, we need to think more broadly about elbows than just the elbow x-ray. I'd just like to have some clues about how much more broadly we need to think.

I know that some orthopedists recommend 6 month evaluations so that you can find correctable problems before arthritis develops. If early diagnosis could prevent a life of disability, a 6-month evaluation seems like a good thing to me. I'm considering it for my litter on the ground.

Maybe we could also lower the false positive rate by taking better measures to prevent pediatric injuries. I'm wondering what canine rehabilitation specialists might be able to tell us about prevention of pediatric
injuries. I'm already following Chris Zink's lead
about exercise for my babies. But if I knew more
about how injuries occur, I might have a better idea about how to prevent them.

Another area for exploration might be the contribution
of shoulder and rear structure to overloading elbows.
Mary Roslin Williams wrote something about the fact
that the elbows of American dogs stick out more than
those of English dogs. I think there might be
some important clues in what she said. She really
talked about judging soundness of the whole dog
rather than parts. Perhaps elbow disorders are
heritable in ways different from what can be judged
strictly by an elbow x-ray.

I'm trying to figure out how I can use her advice
to lower the rate of elbow problems in dogs I breed.
One of the reasons I liked Joshie as a sire was the
fact that he came from a sire and dam who were both
very active dogs with great structures and movement, and who have been sound dogs into adult life. I found the soundness of his parents to be more compelling than his normal elbow evaluation.

So as I'm spending a lot of time observing those
precious lives in my bathroom, I'm thinking about
their little elbows. (Yes, getting a bit more rest
too. Wink.)

We've got some cute pictures coming soon. Hubbie took a course on documentary film work and he seems to be making a video of the puppies for his next class this fall. Kate

Re: ED - what are the REAL facts?

Kate, Mary Roslin-Williams made the observation about the elbows on American Labradors compared to the British more than 30 years ago in April, 1976. I think that point should be made clear.

Re: ED - what are the REAL facts?

The first solid, factual and sane comment in this thread. Thank you MSW.

Re: ED - what are the REAL facts?

"I'm already following Chris Zink's lead
about exercise for my babies."

Kate, could you elaborate on this please, i.e. age, frequency, and type of exercise? Thanks.

Re: ED - what are the REAL facts?

Margaret, Do you think that things are different now
than 30 years ago in regard to elbows? I actually have heard judges make similar comments now about "out at the elbows." Of course, I have also heard judges talk about being "tied in" at the elbows and talk about straight shoulders and rears, which I may also play a role in elbow overloading.

But I wasn't actually implying that MRWs comments about elbows sticking out were the "clue" to understanding elbow issues but more that elbow structure in the context of the whole body and even whole dog was the "clue." She has written about evaluating the whole dog several
times and about overall soundness.

Kate

Re: ED - what are the REAL facts?

Maria, What age baby are you wanting? At the moment,
my mind is stuck at 3-16 week olds. But I am planning ahead for the next several months in which I have the litter. I talked with Chris about what we're doing, and she thought it appropriate for puppies we're raising.

We have constructed tiny agility equipment (e.g., dog walk, tunnels, teeter boards, stairs for climbing) that has safety built into it by virtue of its size
and safety rails. No falls really possible. We also start swimming lessons in our pond, which we constructed so that puppies could walk into the water easily; we block use of the dock.

Their agility equipment play areas are packed sand, easy for walking but still soft for falling. (They also like to dig in the sand). They also have a grassed play area. No concrete or asphalt anywhere.

Puppies are supervised most of their time outdoors,
and we enforce some rest times so no one can get
overtired.

We continue this approach with the litter for the
four months we have them and then continue with the ones we keep. Weather permitting, we encourage
swimming in order to discourage high-impact activities on the ground.

Until they are about 9 months old, the only leash walking we do is in the house or a round pen. We can
practice the skill of being on a leash without actually walking them. They never need to walk on
leash. Chris recommended waiting until puppies are
at least 6 months old before walking them on leash; we find that 9 month is a better time to start from a training standpoint. No running on leash until 24 months old. We never ever try to
"tire out" a puppy. We restrict the amount of exercise so that the puppy never gets very tired; lots of injuries occur when animals are tired

We monitor puppy weights regularly by weighing and
correcting food amounts so that they don't grow too fast.

We do lots and lots of supervision of play. I don't just turn them out to play alone, any more than I
would let small children play unsupervised on a playground. No playing with large older dogs unless
we are mighty sure about how the older dog will
interact with the puppies. We have one large male
who is exceptionally careful with puppies and helps
us with swimming lessons by letting the puppies
ride him and use him like a life preserver.

Puppies are most vulnerable to injuries before growth
plates are closed (and there are growth plates in the bones of the elbows just like other places) and joints
(ligaments, tendons, etc.) are forming. Growth plates
close at different times throughout the body; my
understanding is that the elbow joint is most
vulnerable in the first 6 months to injury during
growth.

I'm putting together stuff for puppy exercise as
I learn it. I've consulted Chris and another
rehab specialist and a vet orthopedist at the
vet school in our area. I've taken some
weekend courses from Chris as well. My current
area of interest is elbows so I'm going to do another
round of consultations this fall about elbows.

Re: ED - what are the REAL facts?

Who do you think is going to get the last word?

Re: Re: ED - what are the REAL facts?

Who knows? This whole thread has taught me never to try arbitration again. I have learned my lesson.

Re: ED - what are the REAL facts?

Elbow replacement surgery for dogs with arthritic ED.

http://petloverstips.com/ForTheLoveoftheDog/news-updates/dog-undergoes-rare-surgery-for-arthritis-video

Re: ED - what are the REAL facts?

Thanks so much for posting this video. Amazing stuff.
I sure hope that others see it because it sounds like
they are still enrolling dogs for the clinical
trials. Perhaps you should post this on another
thread so that it gets the attention it deserves.

Again, thanks for the post. I'm going to call this
guy so that I can talk to him about elbows generally.

Kate