have 4 pups in a 9 week old litter that received 5 way shots at 6 weeks and 7 way at 8 weeks by vets last Thursday.
One of these pups became sick two days ago, testing positive for parvo.

I have 8 pups in a 6 week old litter that have had any vaccines yet.

Please someone give me the dosage for Tamiflu so my vet can call me in a prescription.

I don't know but could ask my vet when they open this a.m. I'm surprised your vet doesn't know??? Hope the pups are okay & someone who knows this info posts ASAP.

I think it was 5cc per 10lbs but not for sure. I had this happen a few months ago. I will tell you what I did was bleach everything I could and not go where the puppies are and then anywhere else. wash your cloths and hands 1000 times. have one pair of shoes for the area you are going to have them in. I lost the girl I took to the vet so when the next 3 got sick i had my vet put an IV in their leg took them home with several bags of fluids. I gave them 100ml every hour or 2. Get them a shot of antibiotics. As soon as one looks like it does not want to eat or drink even if they look fine start them on a drip. The Iv gets clogged after about 2 or 3 days so had to have new ones put in. My vet did not do the tamiflu so i did not use it just kept more than enough fluids and antibiotics. the only thing I ever got them to eat was dry puppy food warm water with a packet of probiotics sprinkled in it. Saved all 3 puppies. Good luck and i am so sorry.

Ok first off, thats way too many vaccines, way too close together - PS Lab pup should never get Lepto that young.
Second, a pup will test pos. for parvo soon after receiving a parvo vaccine, from what I have heard.

how is vaccines at 6 and 8 weeks old to many?

I have used that schedule for years for good reason.
Warmer climates tend to get hit with parvo much harder than northern folks.

tamiflu dosage is .5 ml or 1/2 ml per 10lbs. Given 2 times a day for 5 days. It seems to be a hit or miss treatment, good luck with your kids

I purchased the tamilflu and gave all pups morning dosage. Crossing my fingers other pups will be fine.
took some back to the vets so they can give some to the pup. We were surprised it came back parvo, no smell, no blood, just off food.
My vet had never heard of using Tamiflu, so this will be a test run for her.

to clarify things, I always give 5 way pup shot at 6 weeks old. Vet must give 8 way (no lepto) at 8 weeks when we want the required state health certificate.

My younger litter was suppose to receive their 6 week old vaccines tomorrow.

pups are kept in large inside outside kennel runs that are washed twice daily with a bleach solution up to a week ago when I got a wysiwash sprayer.

all bowls and toys go into a sink full of bleach water daily. we use the 3 gallon chick waters so they can not step into it and contaminate.
all blankets are washed in bleach every other day.

counting back would put me just after Christmas when I had some families come to visit pups. That will change in the future.

thank you for the dosage, dreading the next few days

Glad you got the meds into them & I'll be hoping everything turns out okay!!!

Tamiflu won't help your puppies!

information on tamiflu, seems the dosage must be doubled for pups with symptons.
good luck


On April 24, 2004, the concept of treating Parvoenteritis in dogs
with a neuraminidase inhibitor (Tamiflu) was introduced on the
Veterinary Information Network's Infectious Disease Board. Since then,
Tamiflu has been used successfully by veterinarians, shelter workers
and rescue groups to treat Parvoenteritis in thousands of dogs, cats
and raccoons throughout the world.

Tamiflu: Oseltamivir is one of two commercially available sources of a
neuraminidase inhibitor that has been used successfully in treating
infectious parvoenteritis.

Neuraminidase: An enzyme that is produced by both bacteria and
viruses. It is considered a virulence factor in viral and bacterial
infections that require neuraminidase to remove biological barriers
that protect the host.

Super infections: Any infection that requires both a virus and
bacteria to produce an infection that is more pathogenic than either
infectious agent can produce alone. Veterinary examples: canine and
feline Parvo, canine kennel cough and influenza, feline URI,
parvoenteritis in raccoons, and bloody scowls in deer.

The use of Tamiflu in canine, feline, and raccoon parvoenteritis: The
success of using a neuraminidase inhibitor in treating canine and
feline Parvo is due to the suppression the production of bacterial
neuraminidase, and has no effect on the Parvovirus' ability to
replicate. Puppies can still develop myocarditis and CHF...kittens can
still develop cerebellar hypoplasia...the patient's feces will still
contain the viral antigen even while the animal is recovering. Tamiflu
does not interfere with the replication of the Parvovirus, and as a
result, no mutant or resistant strains of the Parvovirus will be
created from the use of Tamiflu.

Tamiflu should never be used to treat any animal that does not test
(+) using the fecal antigen test. All of the guidelines for using
Tamiflu have been developed in cases that have had a (+) fecal Parvo test.

Dose: 1mg/lb that dose given every 12 hours for 10 consecutive
treatments...requires a (+) fecal antigen test.... There is a direct
relationship between clinical response and the time treatment is
started…Tamiflu should be given w/in 48 hrs of onset of clinical
signs...if no response after the first dose...double to 2mg/lb for the
second, third dose, etc.

Specific Breeds of Dogs: Dobies, Rotties, Retrievers, Pit Bulldogs,
and Alaskan sled dogs...all require at least 2mg/lb as the starting
dose as these breeds respond poorly to Parvo infections...

As a preventive: Animals have been exposed, but are not currently
showing any clinical signs should be given 1mg/lb once a day for 5
days...if these animals develop one or more clinical signs
(vomiting/bloody diarrhea/anorexia)...treatment should be changed so
that they are given 1mg/lb every 12 hr for a total of 10 treatments.

Animals requiring IV support: Animals sick enough to require IV
support (fluids/antibiotics/antiemetics) respond poorly to Tamiflu.
Their clinical condition is the result of a damaged GI tract with the
introduction of GI bacteria and toxins beyond Tamiflu's ability to
protect the patient. If used, Tamiflu can be started at 2mg/lb and the
dose adjusted according to the patient's response every 12 hours.

Animals that vomit after being given oral Tamiflu: These patients can
be given the same dose as an enema. You can also divide the contents
of a 75mg capsule into lines and mix the appropriate amount into
pancake syrup or honey and place under the tongue or in the lip fold.

Tamiflu Products: There is a suspension that you add 23 cc of water to
get 25cc of 12mg/cc. There is also a flat of ten 75 mg capsules.

To use capsules to treat a 5 lb puppy: Mix the contents of 1 capsule
into 10 cc of a liquid diet like Canine Rebound...this will create a
10cc suspension with a concentration of 7.5mg/cc....Refrigerate and
shake well and give 1cc q. 12 hrs x 10 treatments.... do not mix
capsules with water as this water suspension is very bitter and can
cause the patient to vomit. One can also use liquid VAL or similar
vitamin prep.

To use the suspension (12mg/cc) to treat a 5 lb puppy: Shake well and
give the puppy 0.5cc of the suspension q. 12 hrs x 10 treatments.
Refrigerate the suspension after adding water and between treatments.

Tamiflu and FDA: On March 20, 2006, the FDA banned the use of Tamiflu
and other neuraminidase inhibitors in treating chickens, ducks,
turkeys and other birds...goes into effect in June 2006.... you can
still use Tamiflu in dogs, cats, and raccoons.

In the emergency clinics or private clinics that are presented with
cases whose disease course is unknown or have exceeded the 48 hrs
time-frame: The professional staff should make the client aware of the
poor response to Tamiflu due to the high levels of bacterial
neuraminidase currently present in the patient's GI tract, and the
presence of GI pathology created prior to presentation. Tamiflu will
only prevent future pathology, and cannot reverse any pathology
created prior to treatment.

Treating Parvo requires the same mental process used in treating
Diabetes Mellitus.... The DVM begins with a standard initial dose of
Tamiflu or insulin and then uses professional judgment to adjust the
following doses required to get a clinical response.

In an uncomplicated case, presented within 48 hrs. of the onset of
clinical signs, one should see no vomiting after the first dose...no
diarrhea after the 2nd...and alert/eating after the 3rd dose. If there
is no clinical response after the 3rd dose...you have either started
using Tamiflu too late, have a secondary medical problem that needs to
be addressed, or have the wrong diagnosis.

In summary, the introduction of the concept of using a neuraminidase
inhibitor to treat canine, feline and raccoon Parvoenteritis, has
opened many new doors into the understanding of the pathobiology and
treatment of this disease. Prior to April 24, 2004, Parvovirus was
thought of as viral enteritis. Based on this concept, vaccines were
developed to help prevent or reduce the severity of the clinical disease.

Once the disease was diagnosed, treatment protocols were all designed
to address the various end products produced during the disease. The
presence of vomiting and/or diarrhea usually dictated that most drugs
were given intravenously. Animals that are hospitalized usually remain
3-7 days with unpredictable prognosis. This is because none of the
treatments address the core problem of excessive GI bacterial
neuraminidase. Drugs are given to address all of the various reactions
such as: vomiting, endotoxic shock, pain, bacterial septicemia, GI
mucosal ulcerations and general organ failure. This approach requires
many drugs and man-hours to treat the multiple pathological processes
associated with viral Parvoenteritis.

With the introduction of using a neuraminidase inhibitor (Tamiflu), we
established that Parvoenteritis is not a viral enteritis, but a super
infection that requires the presence of bacterial neuraminidase. When
a neuraminidase inhibitor is use under the strict guidelines developed
since April 24, 2004, the disease is not allowed to develop into the
clinical disease currently known as viral Parvoenteritis. The
commensal bacteria do not transform into pathologic bacteria, and the
patient's disease is not allowed to progress as described in the
veterinary literature. In order to achieve this reversal, there has to
be a definitive diagnosis and the neuraminidase has to be given
according to established guidelines.

Please keep in mind that any recommendations given in this article are
not FDA approved. They are offered to help educate and guide those
anticipating using Oseltamivir therapy in the future. Roadrunner
Pharmacy is currently in the process of acquiring Oseltamivir powder
to be compounded into the various formulations and concentrations
requested by our clients.

To insure the continual gathering of clinical data, please contact
Jack J. Broadhurst, DVM at doccat@aol.com or fax at 910-295-2265.
There is a clinical trial form that if filled out and returned, will
insure a central point for clinical results to be stored. He can also
be contacted at 910-295-2287.

Jack J. Broadhurst, DVM The Cat Health Clinic 2212 Midland Road
Pinehurst, NC 28374

What kind of 8 way vaccine is there that doesn't have Lepto????
Proguard 8 is this - Canine Distemper, Adenovirus Type 2, Coronavirus, Parainfluenza, Parvovirus vaccine Modified Live Virus and killed virus. (CPV Strain 154) Leptospira Bacterin

And as far as full vaccinations at 6 and 8 weeks, I have never heard of this?
Potocal says vaccinate every 3-4 weeks.
Is this different in different areas?

lab breeder did not say she gave an 8 way shot. He said they gave a 7 way AT 8 weeks.

I am in Florida and it is common to give vaccines at 6 weeks and 8 weeks before pups go home. We are a warm state and parvo is forever a threat all year long.

Just keep an eye on the ones that are at this time just not eating. That was when I started mine on an IV drip just to get ahead of the dehydration. I am sure you know that they do not die from Parvo but from an infection and or dehyration.