Just been looking on a website at a choc dog from the USA whose coat colour DNA test result says "bs bs". Anybody know what bs means in terms of coat colour genetics? I thought that the only letters involved in Lab colour inheritance were B, b, E and e ??????
I'd ask the person with the dog and/or website. S is often Solid and s is spotting factor in most dog breeds. A small white spot on chest is permitted, but not desirable, and is noted in link below as s1. The link has been cited many times on this forum. Famous Labs seem to have carried a gene for a white spot or white foot in recent history, as well as in far past.
There are several reasons a dog may be brown instead of black. Three of these are routinely checked by most DNA tests today. The first is a premature stop codon at amnino acid 331. It is noted as bs. The second is a three-neuclotide deletion at residue 345. This is noted as bd. The third common one is a substitution of serine for a cysteine. This is usually noted as bc. Several of the DNA laboratories are now noting the type of "brown" coding found in the DNA.
If a dog has two of these genes in pairs or combination, it is generally brown. The dog could be bs/bd or bs/bs or other combinations. It is calculated that a dog with more than two of these markers is statistically more likely to produce brown offspring when mated with a carrier due to the increased percentage chance of passing on more than one type of the brown genes.
