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EIC Carrier

If a dog comes back as an EIC Carrier, does that mean that both parents are at least Carriers? I can't seem to find a chart online that explains the breakdown of breeding clear to clear or clear to carrier, etc.
Thanks

Re: EIC Carrier

as of right now, the explanation is simple recessive.

That meaning in order to have a carrier, one parent at least must carry the gene.

Both parents might be carriers, one clear/one carrier, or one affected/one clear.

But someone carries that gene.

Re: EIC Carrier

small scale
as of right now, the explanation is simple recessive.

That meaning in order to have a carrier, one parent at least must carry the gene.

Both parents might be carriers, one clear/one carrier, or one affected/one clear.

But someone carries that gene.


could also be one Affected/one Carrier, but you are right - at least one parent has the gene.

Re: EIC Carrier

No, It can happen from a carrier and a clear. Also from 2 carriers and a carrier and an affected. Never from 2 affected or 2 clear

Re: EIC Carrier

Here's the link to an inheritance chart. Explains everything. Even though this is DDC's chart for coat, the same principles apply to EIC and other inherited diseases that are recessives...

http://www.vetdnacenter.com/images/fluffy-chart.jpg

Re: EIC Carrier

This chart is (obviously) the chart for breeding strategies for PRA, but the mode of inheritance is (allegedly) the same for EIC, a simple recessive. It might help you to visualize this punnet square, just substitute EIC clear, carrier and affected, for the PRA status. :-)

http://www.optigen.com/opt9_test_prcdprabs.html

Re: EIC Carrier

Or from the EIC website at the U of MN:

http://www.vdl.umn.edu/prod/groups/cvm/@pub/@cvm/@vdl/documents/asset/cvm_asset_107687.pdf

Re: EIC Carrier

http://www.vdl.umn.edu/prod/groups/cvm/@pub/@cvm/@vdl/documents/asset/cvm_asset_107687.pdf

I could only read the full url when quoting it, so here is the *link* .

Re: EIC Carrier

From what she was asking. One parent could be clear and one a carrier. Or both carriers, or one effected and one a carrier. Right ? Trying to stay in layman words.

Re: EIC Carrier

Breeder also
From what she was asking. One parent could be clear and one a carrier. Or both carriers, or one effected and one a carrier. Right ? Trying to stay in layman words.


All the above possibilities are correct.

Re: EIC Carrier

There are already so many explanations and links that you should be on top of this by now. Here is just one way to think about a dog that is tested as a carrier for any RECESSIVE trait. The dog got one recessive gene for that trait from somewhere. That means at least one of the parents had to have at least one gene for the trait. Since the dog also has one dominant gene for the "normal" status, the same applies. At least one of the parents has to have at least one dominant gene for normal. Any combination that allows for at least one of the dominant and one of the recessive genes can give you the outcome you asked about. Does that make it simpler?

Re: EIC Carrier

Thanks so much everyone. The chart(s) were exactly what I was looking for. I posted the original post because I was told since the dog came back a carrier that, with EIC, both parents had to be carriers but I was pretty sure that EIC followed the same idea as the OptiGen tests.... that one partent was obviously at least a carrier BUT the other parent could be clear. Thanks GTF, your explanation was very helpful as well!! So thanks again for all the input