can someone tell me the percentage of a dog being optigen affected/carrier where the dog's grandsire is on the carrier list already published? much appreciated
If there are no other carriers in the pedigree, then the dog has a 25% chance of being a carrier. Probability of the grandparent passing it to the parent = .5. Probability of a parent passing thatgradparent's gene to the dog = .5. These are two independent events, so the probability of both happening is .5 X .5 = .25, or 25%