The current Optigen test is for the most common type of PRA. There are other types. Look at the Optigen website at www.optigen.com. If one parent is clear through Optigen, and the dog is clearly blind, it would be from another condition and not the type of PRA covered by the test.
Yes.... and no. The test is for prcd-PRA. There are other things that cause blindness - and some are not even retinal. The second possibility is that the tested clear dog is NOT the actual parent of the blind one. There have been about a half-dozen challenges to the OptiGen test and so far they have fallen into this second category. After testing the sire and the offspring with the Optigen test, they then compare DNA parentage markers and have found the supposed sire to not be the actual sire. If you think this can't happen to you, look at the number of registrations cancelled or corrected every month in the Gazette for just that reason.
I would hope not but no test is 100% fullproof and if there was an error in the test or another type of PRA involved than the test tests for then all things are possible....
Aloha,
jackie