probably no help....but did she run bloodwork? Specifically for tick born illnesses? I am in Virginia and my vet was just telling me last week that they are seeing a ridiculously high number of Ehrlicia patients.
Many tick borne diseases can cause stiffness and swelling in the wrist (carpus). Some can cause clotting issues as well. She might want to have her Vet run a "Tick Panel" Best of luck!