Depends on the age. I feed at 3 weeks no matter what. I have started as early as 2 1/2 weeks. At 4 weeks, my pups would be starving. If the pups have teeth, make sure mom has a way to get away from them. Do not leave her locked up with a box full of piranhas.
Consider this, I work so I wake up early and give puppies an early morning feed. I feed again 3-4 hours later when I leave for work. I feed them as soon as I get home from work and another meal 3-4 hours later just before I go to bed late. It has worked for me. Yes I loose a little sleep for a few weeks but my puppies are happy any healthy and mom is not overworked supplying the milk bar 24/7.
It is the trade off I make as someone who works yet still enjoys a itter once in a while.
